Probiotics and prebiotics: new treatment strategies for oral potentially malignant disorders and gastrointestinal precancerous lesions
Zhuwei Huang, Jiaye Zhu, Xiaobo Bu, Shulai Lu, Yingxian Luo, Ting Liu, Ning Duan, Wenmei Wang, Yong Wang, Xiang Wang
Abstract
Oral potentially malignant disorders (OPMDs) and gastrointestinal precancerous lesions (GPLs) are major public health concerns because of their potential to progress to cancer. Probiotics, prebiotics, and engineered probiotics can positively influence the prevention and management of OPMDs and GPLs. This review aims to comprehensively review the application status of probiotics, prebiotics and engineered probiotics in OPMDs and GPLs, explore their potential mechanisms of action, and anticipate their future clinical use.
Topics & Concepts
MedicinePrecancerous conditionDermatologyGastroenterologyInternal medicineCancerDigestive system and related healthProbiotics and Fermented FoodsMicrobial Metabolites in Food Biotechnology