Curcumin loaded zinc oxide nanoparticles for activity-enhanced antibacterial and anticancer applications
W. P. T. D. Perera, Ranga Dissanayake, U. I. Ranatunga, N. M. Hettiarachchi, Kalindu Perera, Janitha M. Unagolla, R. T. De Silva, Lakshitha Pahalagedara
Abstract
MTT assay, while their cytotoxic effects were tested against human embryonic kidney cells using the resazurin assay. SZNP-Cs exhibited the best balance between the two, showing the lowest toxicity against healthy cells and good anticancer activity. The results of this investigation demonstrate that the nanomatrix synthesized can act as an effective, additively-enhanced combination delivery/therapeutic agent, holding promise for anticancer therapy and other biomedical applications.
Topics & Concepts
CurcuminNanoparticleZincChemistryAntibacterial activityCombinatorial chemistryNuclear chemistryNanotechnologyMaterials scienceOrganic chemistryBiochemistryBacteriaBiologyGeneticsCurcumin's Biomedical ApplicationsNanoparticles: synthesis and applicationsNanoparticle-Based Drug Delivery