[Rh(COD)Cl]<sub>2</sub>/PPh<sub>3</sub>-Catalyzed Dehydrogenative Silylation of Styrene Derivatives with NBE as a Hydrogen Acceptor
Wenkui Lu, Chengyang Li, Xiaoyu Wu, Xiaomin Xie, Zhaoguo Zhang
Abstract
Direct synthesis of arylalkenylsilanes by [Rh(COD)Cl]2/PPh3-catalyzed dehydrogenative silylation of styrene derivatives with R3SiH (R = alkyl, alkoxy, aryl) was realized, in which norbornene (NBE) and PPh3 play a key role in achieving excellent selectivity in the formation of dehydrogenative silylation products. Moreover, this high-yielding transformation exhibits a broad substrate scope and good functional group tolerance.
Topics & Concepts
ChemistrySilylationAlkylStyreneAlkoxy groupArylCatalysisMedicinal chemistryNorborneneSelectivityOrganic chemistryPolymerizationCopolymerPolymerCatalytic C–H Functionalization MethodsCatalytic Cross-Coupling ReactionsOrganoboron and organosilicon chemistry