Discovery of a novel photoswitchable PI3K inhibitor toward optically-controlled anticancer activity
Yan Zhang, Shouguo Peng, Songwen Lin, Ming Ji, Tingting Du, Xiaoguang Chen, Heng Xu
Topics & Concepts
ChemistryAzobenzenePI3K/AKT/mTOR pathwayMoietyZebrafishEnantiomerStereochemistryBiophysicsBiochemistrySignal transductionMoleculeOrganic chemistryBiologyGenePhotochromic and Fluorescence ChemistryPhotoreceptor and optogenetics researchNanoplatforms for cancer theranostics