Role of IL-17 and IL-23 in the Pathogenesis of Neutrophilic Asthma
Nightingale Syabbalo
Abstract
Asthma is a complex chronic airway disease with several distinct phenotypes characterized by different immunopathological pathways, clinical presentation, physiology, comorbidities, biomarker of allergic inflammation, and response to treatment. Approximately 10% of patients with asthma have severe refractory disease, which is difficult to control on high doses of inhaled corticosteroids and other modifiers. About 50% of these individuals suffer from neutrophilic asthma.
Topics & Concepts
AsthmaPathogenesisMedicineBiomarkerImmunologyInflammationDiseaseAirwayRefractory (planetary science)Internal medicineBiologyAstrobiologyBiochemistrySurgeryAsthma and respiratory diseasesPediatric health and respiratory diseases