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Nrl Is Dispensable for Specification of Rod Photoreceptors in Adult Zebrafish Despite Its Deeply Conserved Requirement Earlier in Ontogeny

A. Phillip Oel, Gavin J. Neil, Emily Dong, Spencer D. Balay, Keon Collett, W. Ted Allison

2020iScience24 citationsDOIOpen Access PDF

Abstract

null mutant zebrafish. Rods developed in adults despite Nrl protein being undetectable. Therefore, a yet-to-be-revealed non-canonical pathway independent of Nrl is able to specify the fate of some rod photoreceptors.

Topics & Concepts

ZebrafishOntogenyCell biologyBiologyDevelopmental biologyEvolutionary biologyAnatomyGeneticsGeneRetinal Development and DisordersPhotoreceptor and optogenetics researchZebrafish Biomedical Research Applications