A plasma membrane-associated glycolytic metabolon is functionally coupled to KATP channels in pancreatic α and β cells from humans and mice
Thuong Ho, Evgeniy Potapenko, Dawn Belt Davis, Matthew J. Merrins
Abstract
-controlling glycolytic signaling complex and demonstrate its relevance to islet glucose sensing and excitability.
Topics & Concepts
GlycolysisGlucokinasePhosphofructokinaseBiochemistryCell biologyChemistryGlyceraldehyde 3-phosphate dehydrogenasePyruvate kinaseBiologyInternal medicineDehydrogenaseEnzymeMedicinePancreatic function and diabetesCannabis and Cannabinoid ResearchHyperglycemia and glycemic control in critically ill and hospitalized patients