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The genome of a hadal sea cucumber reveals novel adaptive strategies to deep-sea environments

Guangming Shao, Tianliang He, Yinnan Mu, Pengfei Mu, Jingqun Ao, Xihuang Lin, Lingwei Ruan, YuGuang Wang, Yuan Gao, Dinggao Liu, Liangsheng Zhang, Xinhua Chen

2022iScience33 citationsDOIOpen Access PDF

Abstract

may maintain cell membrane fluidity. Second, three genes for translation initiation factors and two for ribosomal proteins underwent expansion, and three ribosomal protein genes were positively selected, which may ameliorate the protein synthesis inhibition or ribosome dissociation in the hadal zone. Third, expansion and positive selection of genes associated with stalled replication fork recovery and DNA repair suggest improvements in DNA protection. This is the first genome sequence of a hadal invertebrate. Our results provide insights into the genetic adaptations used by invertebrate in deep oceans.

Topics & Concepts

BiologyGenomeRibosomeGeneRibosomal RNARibosomal proteinGeneticsRNAEchinoderm biology and ecologyMarine Bivalve and Aquaculture StudiesCoral and Marine Ecosystems Studies