Design, synthesis, and structure activity relationship analysis of new betulinic acid derivatives as potent HIV inhibitors
Yu Zhao, Chin‐Ho Chen, Susan L. Morris‐Natschke, Kuo‐Hsiung Lee
Topics & Concepts
Betulinic acidChemistryNatural productStructure–activity relationshipLead compoundStereochemistryEC50Human immunodeficiency virus (HIV)PharmacologyCombinatorial chemistryIn vitroBiochemistryVirologyBiologyGeneticsHIV/AIDS drug development and treatmentNatural product bioactivities and synthesisBiochemical and Molecular Research