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Novel HIF-1α Inhibitor AMSP-30m Mitigates the Pathogenic Cellular Behaviors of Hypoxia-Stimulated Fibroblast-Like Synoviocytes and Alleviates Collagen-Induced Arthritis in Rats via Inhibiting Sonic Hedgehog Pathway

Li Cai, Bo Meng, Fei Jiang, Wenhao Shu, Xiao Hua Wang, Mengqing Wang, Xinjie Wu, Ming-wang Hu, Yu‐Chen S. H. Yang, Xiang Ran, Rong Li

2023Inflammation18 citationsDOI

Topics & Concepts

CyclopamineApoptosisChemistryHedgehog signaling pathwayArthritisCancer researchHypoxia (environmental)Cell cyclePharmacologyCell biologyImmunologySignal transductionBiologyBiochemistryOrganic chemistryOxygenCancer, Hypoxia, and MetabolismCancer-related molecular mechanisms researchRNA modifications and cancer
Novel HIF-1α Inhibitor AMSP-30m Mitigates the Pathogenic Cellular Behaviors of Hypoxia-Stimulated Fibroblast-Like Synoviocytes and Alleviates Collagen-Induced Arthritis in Rats via Inhibiting Sonic Hedgehog Pathway | Litcius