Progerin induces a phenotypic switch in vascular smooth muscle cells and triggers replication stress and an aging-associated secretory signature
Núria Coll-Bonfill, Urvashi Mahajan, Elena V. Shashkova, Chien‐Jung Lin, Robert P. Mecham, Susana Gonzalo
Topics & Concepts
ProgeriaVascular smooth muscleBiologyLMNACell biologyPhenotypeGenome instabilityLaminTelomereCancer researchDNA damageGeneticsEndocrinologyGeneDNANucleusSmooth muscleNuclear Structure and FunctionRetinoids in leukemia and cellular processesUbiquitin and proteasome pathways