M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome
Sahana D. Rao, Qifeng Chen, Qinghui Wang, Elizabeth L. Orth-He, Michelle Saoi, Andrew R. Griswold, Abir Bhattacharjee, Daniel P. Ball, Hsin‐Che Huang, Ashley J. Chui, Dominic J. Covelli, Shaochen You, Justin R. Cross, Daniel A. Bachovchin
Topics & Concepts
InflammasomeAminopeptidaseIntracellularEnzymeDipeptidyl peptidaseNLRP1BiochemistryBiologyPeptideCell biologyChemistryAmino acidReceptorCaspaseLeucineProgrammed cell deathApoptosisPeptidase Inhibition and AnalysisSignaling Pathways in DiseaseGalectins and Cancer Biology