Litcius/Paper detail

M24B aminopeptidase inhibitors selectively activate the CARD8 inflammasome

Sahana D. Rao, Qifeng Chen, Qinghui Wang, Elizabeth L. Orth-He, Michelle Saoi, Andrew R. Griswold, Abir Bhattacharjee, Daniel P. Ball, Hsin‐Che Huang, Ashley J. Chui, Dominic J. Covelli, Shaochen You, Justin R. Cross, Daniel A. Bachovchin

2022Nature Chemical Biology36 citationsDOIOpen Access PDF

Topics & Concepts

InflammasomeAminopeptidaseIntracellularEnzymeDipeptidyl peptidaseNLRP1BiochemistryBiologyPeptideCell biologyChemistryAmino acidReceptorCaspaseLeucineProgrammed cell deathApoptosisPeptidase Inhibition and AnalysisSignaling Pathways in DiseaseGalectins and Cancer Biology