3D printing of MXene composite hydrogel scaffolds for photothermal antibacterial activity and bone regeneration in infected bone defect models
Ran Nie, Yue Sun, Huixin Lv, Ming Lu, Huimin Huangfu, Yangyang Li, Yidi Zhang, Dongyang Wang, Lin Wang, Yanmin Zhou
Abstract
-infected mandible defects of rats with NIR irradiation. GTAM scaffolds could accelerate the healing of infection and bone regeneration, and play synergistic roles in antibacterial and osteogenic effects. This study not only provides a strategy for the precise osteogenesis of infected bone defects, but also broadens the biomedical applications of MXene photothermal materials.
Topics & Concepts
ScaffoldBiocompatibilityMaterials scienceOsseointegrationBiomedical engineeringPhotothermal therapyRegeneration (biology)In vivoBone healingMesenchymal stem cellComposite numberImplantNanotechnologyComposite materialCell biologyAnatomyMedicineSurgeryBiologyMetallurgyBiotechnologyNanoplatforms for cancer theranosticsMXene and MAX Phase MaterialsBone Tissue Engineering Materials