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Predominant intermolecular decarbonylative thioetherification of carboxylic acids using nickel precatalysts

Haiyao Ji, Han Cao, Guan Wang, Feifei Xing, Michal Szostak, Chengwei Liu

2023Organic Chemistry Frontiers17 citationsDOI

Abstract

We report a general method for direct decarbonylative thioetherification of carboxylic acids using air- and moisture-stable nickel precatalysts. In this approach, ubiquitous carboxylic acids are directly used as aryl electrophiles and common thiols serve as sulfide donors.

Topics & Concepts

ChemistryElectrophileArylNickelSulfideCarboxylic acidIntermolecular forceOrganic chemistryCatalysisMoleculeAlkylSulfur-Based Synthesis TechniquesChemical Synthesis and ReactionsOrganoselenium and organotellurium chemistry