Design, synthesis, bio-evaluation, and <i>in silico</i> studies of some N-substituted 6-(chloro/nitro)-1<i>H</i>-benzimidazole derivatives as antimicrobial and anticancer agents
Em Canh Pham, Tuong Vi Thi Le, Tuyen Ngoc Truong
Abstract
is the most suitable target for both antimicrobial and anticancer activities, and vascular endothelial growth factor receptor 2 and histone deacetylase 6 are the most suitable targets for anticancer activity of these potent compounds.
Topics & Concepts
BenzimidazoleAntimicrobialNitroChemistryCombinatorial chemistryIn silicoStereochemistryOrganic chemistryBiochemistryAlkylGeneSynthesis and biological activityComputational Drug Discovery MethodsBioactive Compounds and Antitumor Agents