Self-assembled lyotropic liquid crystal gel for osteoarthritis treatment <i>via</i> anti-inflammation and cartilage protection
Liling Mei, Hui Wang, Jintian Chen, Ziqian Zhang, Feng Li, Yecheng Xie, Ying Huang, Tingting Peng, Guohua Cheng, Xin Pan, Chuanbin Wu
Abstract
degradation behavior and the intra-articular irritation results of LLC/HLC gel demonstrated that it was biodegradable and biocompatible. These results collectively demonstrated that HLC gel with anti-inflammation and cartilage protection performance provides a useful approach to treat OA.
Topics & Concepts
OsteoarthritisCartilageHyaluronic acidInflammationThixotropyIn vivoArthritisDrug deliveryNanocagesMaterials scienceChemistryBiomedical engineeringMedicineNanotechnologyInternal medicinePathologyBiochemistryComposite materialAnatomyCatalysisAlternative medicineBiotechnologyBiologyOsteoarthritis Treatment and MechanismsProteoglycans and glycosaminoglycans researchOcular Surface and Contact Lens