Increased expression of ACE2, the SARS-CoV-2 entry receptor, in alveolar and bronchial epithelium of smokers and COPD subjects
Merel Jacobs, Hannelore P. Van Eeckhoutte, Sara Wijnant, Wim Janssens, Guy Joos, Guy Brusselle, Ken R. Bracke
Abstract
<b>This study demonstrates increased protein levels of ACE2 in alveolar and bronchial epithelium of smokers and subjects with COPD, which might facilitate host cell entry of SARS-CoV-2</b>https://bit.ly/2ZazOrd
Topics & Concepts
MedicineCOPDReceptorAlveolar EpitheliumEpitheliumSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Respiratory epitheliumCoronavirus disease 2019 (COVID-19)2019-20 coronavirus outbreakRespiratory systemImmunologyInternal medicinePathologyInfectious disease (medical specialty)DiseaseOutbreakSARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research StudiesLong-Term Effects of COVID-19