Synthesis of deuterated S-217622 (Ensitrelvir) with antiviral activity against coronaviruses including SARS-CoV-2
Yujian Yang, Liu Cao, Ming Yan, Jun Zhou, Sidi Yang, Tiefeng Xu, SI-YAO HUANG, Kun Li, Qifan Zhou, Guanguan Li, Yujun Zhu, Feng Cong, Hongmin Zhang, Deyin Guo, Yingjun Li, Xumu Zhang
Topics & Concepts
CoronavirusVirologySevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Coronavirus disease 2019 (COVID-19)ChemistryIn vitroBiologyMedicineBiochemistryInternal medicineInfectious disease (medical specialty)DiseaseChemical Reactions and IsotopesCancer therapeutics and mechanismsthermodynamics and calorimetric analyses