Chemoenzymatic synthesis of fluorinated polyketides
Alexander Rittner, Mirko Joppe, Jennifer J. Schmidt, Lara Maria Mayer, Simon Reiners, Elia Heid, Dietmar Herzberg, David H. Sherman, Martin Grininger
Topics & Concepts
PolyketidePolyketide synthaseChemistryAcyltransferaseAcyl carrier proteinBiosynthesisAcyltransferasesStereochemistryFluorineFatty acid synthaseDrug discoveryCombinatorial chemistryEnzymeBiochemistryOrganic chemistryMicrobial Natural Products and BiosynthesisGenomics and Phylogenetic StudiesSynthetic Organic Chemistry Methods