Cryo‐EM structure of the polyphosphate polymerase VTC reveals coupling of polymer synthesis to membrane transit
Wei Liu, Jiening Wang, Véronique Comte‐Miserez, Mengyu Zhang, Xuejing Yu, Qingfeng Chen, Henning J. Jessen, Andreas Mayer, Shan Wu, Sheng Ye
Topics & Concepts
BiologyProtein subunitCryo-electron microscopyGatingCell biologyTransmembrane domainBiophysicsPolyphosphateIntracellularSaccharomyces cerevisiaeAdenosine triphosphateChaperone (clinical)BiochemistryCrystallographyMembranePhosphateChemistryYeastGeneMedicinePathologyTrace Elements in HealthEndoplasmic Reticulum Stress and DiseaseDrug Transport and Resistance Mechanisms