The orientation of CpG conjugation on aluminum oxyhydroxide nanoparticles determines the immunostimulatory effects of combination adjuvants
Zhihui Liang, Hang Bao, Zhiying Yao, Min Li, Chen Chen, Lei Zhang, Huiyang Wang, Yiyang Guo, Yubin Ma, Xuecheng Yang, Ge Yu, Jiancheng Zhang, Changying Xue, Bingbing Sun, Chuanbin Mao
Topics & Concepts
CpG OligodeoxynucleotideAlumAntigenImmune systemAdjuvantCpG siteBiologyHBsAgAntibodyImmunologyMaterials scienceChemistryBiochemistryHepatitis B virusVirusDNA methylationGene expressionMetallurgyGeneImmunotherapy and Immune ResponsesImmune Response and InflammationRNA Interference and Gene Delivery