SARS-CoV-2 RNA Shedding in Semen and Oligozoospermia of Patient with Severe Coronavirus Disease 11 Weeks after Infection
Lawrence J. Purpura, Joseph P. Alukal, Alexander M. Chong, Lihong Liu, Anyelina Cantos, Jayesh Shah, Nicola Medrano, Jennifer Y. Chang, Moriya Tsuji, Hiroshi Mohri, Anne Catrin Uhlemann, David D. Ho, Michael T. Yin
Abstract
We report severe acute respiratory syndrome coronavirus 2 in semen by using quantitative reverse transcription PCR during the late convalescent phase. Virus was associated with adequate humoral and cell-mediated responses, suggesting possible seeding of the immune-privileged testes. We provide longitudinal semen quality data for 6 other men, including 3 who had oligozoospermia.
Topics & Concepts
SemenViral sheddingCoronavirusSemen qualityVirologyImmune systemBiologyImmunologyCoronavirus disease 2019 (COVID-19)Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)VirusDiseaseMedicineInfectious disease (medical specialty)AndrologyInternal medicineCOVID-19 Impact on Reproduction