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The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis

Renhong Yan, Enjun Xie, Yaning Li, Jin Li, Yuanyuan Zhang, Ximin Chi, Xueping Hu, Lei Xu, Tingjun Hou, Brent R. Stockwell, Junxia Min, Qiang Zhou, Fudi Wang

2022Cell Research189 citationsDOIOpen Access PDF

Abstract

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Topics & Concepts

BiologyComputational biologyCell biologyFerroptosis and cancer prognosisCancer, Lipids, and MetabolismCancer-related molecular mechanisms research
The structure of erastin-bound xCT–4F2hc complex reveals molecular mechanisms underlying erastin-induced ferroptosis | Litcius