Struct-f4: a Rcpp package for ancestry profile and population structure inference from <i>f</i>4-statistics
Pablo Librado, Ludovic Orlando
Abstract
SUMMARY: Visualization and inference of population structure is increasingly important for fundamental and applied research. Here, we present Struct-f4, providing automated solutions to characterize and summarize the genetic ancestry profile of individuals, assess their genetic affinities, identify admixture sources and quantify admixture levels. AVAILABILITY AND IMPLEMENTATION: Struct-f4 is written in Rcpp and relies on f4-statistics and Markov Chain Monte Carlo (MCMC) optimization. It is freely available under GNU General Public License in Bitbucket (https://bitbucket.org/plibradosanz/structf4/). SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Topics & Concepts
structInferenceStatisticsR packagePopulationStatistical inferenceComputer scienceMathematicsArtificial intelligenceProgramming languageDemographySociologyGenetic Associations and EpidemiologyForensic and Genetic ResearchRace, Genetics, and Society