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Soybean protein hydrolysate stimulated cholecystokinin secretion and inhibited feed intake through calcium-sensing receptors and intracellular calcium signalling in pigs

Lvyang Wang, Liren Ding, Weiyun Zhu, Suqin Hang

2021Food & Function27 citationsDOI

Abstract

Intraduodenal infusion of soybean protein hydrolysate (SPH) stimulated cholecystokinin release (CCK) and inhibited feed intake, which was likely due to the activation of calcium-sensing receptor (CaSR) and intracellular Ca 2+ /TRPM5 pathway in pigs.

Topics & Concepts

CholecystokininInternal medicineEndocrinologyAnorecticGastrointestinal hormoneCalcium-sensing receptorPeptide YYAppetiteDuodenumCholecystokinin receptorReceptorChemistryBiologyCalciumHormoneParathyroid hormonePeptide hormoneNeuropeptideMedicineNeuropeptide Y receptorFood intakeMuscle metabolism and nutritionProtein Hydrolysis and Bioactive PeptidesBiochemical effects in animals
Soybean protein hydrolysate stimulated cholecystokinin secretion and inhibited feed intake through calcium-sensing receptors and intracellular calcium signalling in pigs | Litcius