Improved clinical symptoms and mortality among patients with severe or critical COVID-19 after convalescent plasma transfusion
Xinyi Xia, Kening Li, Lingxiang Wu, Zhihua Wang, Mengyan Zhu, Bin Huang, Jie Li, Ziyu Wang, Wei Wu, Min Wu, Wanlin Li, Li Lu, Yun Cai, Bakwatanisa Bosco, Aifang Zhong, Xiong Liu, Tangfeng Lv, Zhenhua Gan, Guang Chen, Yunhu Pan, Caidong Liu, Kai Zhang, Xiaoli Xu, Changjun Wang, Qianghu Wang
Abstract
Two case series examining the impact of convalescent plasma on patients with COVID-19 suggest some clinical benefit from early administration and modest impact on parameters of inflammation. Further assessment of the impact of this intervention awaits controlled clinical trials.
Topics & Concepts
Convalescent plasmaMedicineCoronavirus disease 2019 (COVID-19)Clinical trialIntensive care medicineInternal medicineDiseaseInfectious disease (medical specialty)COVID-19 Clinical Research StudiesLong-Term Effects of COVID-19SARS-CoV-2 and COVID-19 Research