Advancing extrusion-based embedded 3D bioprinting via scientific, engineering, and process innovations
Ezgi Bakırcı, Ali Asghari Adib, Syed Faaz Ashraf, Adam W. Feinberg
Abstract
Extrusion-based embedded 3D bioprinting, where bioinks and biomaterials are extruded within a support bath, has greatly expanded the achievable tissue architectures and complexity of biologic constructs that can be fabricated. However, significant scientific, engineering, and process-related challenges remain to recreate the full anatomic structure and physiologic function required for many therapeutic applications. This perspective explores the future advances in extrusion-based embedded 3D bioprinting that could address these challenges, paving the way for clinical translation of bioprinted tissues.
Topics & Concepts
Extrusion3D bioprintingProcess (computing)Tissue engineeringNanotechnologyFunction (biology)Computer scienceMaterials scienceSystems engineeringManufacturing engineeringBiomedical engineeringEngineeringMetallurgyBiologyOperating systemEvolutionary biology3D Printing in Biomedical ResearchTissue Engineering and Regenerative MedicinePluripotent Stem Cells Research