Generic high-capacity protein capture and release by pH control
Gustav Ferrand‐Drake del Castillo, Rebekah L. N. Hailes, Zeynep Adali-Kaya, Timothy Robson, Andreas Dahlin
Abstract
) immobilization of proteins in polyelectrolyte brushes by multivalent hydrogen bonds. Upon increasing pH, the proteins are fully released with preserved structure and activity.
Topics & Concepts
ChemistryChemical engineeringEngineeringPolymer Surface Interaction StudiesProtein purification and stabilityRNA Interference and Gene Delivery