Revolutionizing Cancer Vaccine: The Power of Advanced Nanotechnology
Saranya Udayakumar, S. Pandiarajan, Devadass Jessy Mercy, J. Immanuel Suresh, Jashwanth Raj Jagadeesh kumar, Agnishwar Girigoswami, Koyeli Girigoswami
Abstract
Developing an effective vaccine that is safer is the main focus in the field of cancer immunotherapy. Among other therapeutic approaches, cancer nanovaccination is formulated to deliver tumor adjuvant or antigen to the antigen-presenting cells (APCs) to prevent cancer relapse and metastasis. It has shown excellent efficacy in inhibiting cancer growth. Herein, we discussed various forms of nanovaccines, including lipid-based nanovaccines, metal-based nanovaccines, carbon nanotube-based nanovaccines, PLGA-based nanovaccines, exosome-based nanovaccines, dendritic cell-based nanovaccines, and self-adjuvant nanovaccines in cancer immunotherapy, including their therapeutic effect. We expect that the investigated content will provide a valuable reference for future research and the development of nanovaccines for cancer treatment.