Unlike estrogens that increase PCSK9 levels post-menopause HSP27 vaccination lowers cholesterol levels and atherogenesis due to divergent effects on PCSK9 and LDLR
Nadia Maarouf, Yong‐Xiang Chen, Chunhua Shi, Jingti Deng, Catherine Diao, Matthew Rosin, Vipul Shrivastava, Zarah Batulan, Jingwen Liu, Edward R. O’Brien
Topics & Concepts
EndocrinologyInternal medicineLDL receptorMedicineCholesterolEstrogenPCSK9Apolipoprotein BMenopauseVaccinationLipoproteinImmunologyHeat shock proteins researchLipoproteins and Cardiovascular HealthProtease and Inhibitor Mechanisms