Biodegradable germanium nanoparticles as contrast agents for near-infrared-II photoacoustic imaging
Pengbo He, Guo Chen, Mengling Huang, Lili Jing, Wen Wu, Hao‐Chung Kuo, Chang‐Ching Tu, Sung‐Liang Chen
Abstract
Novel germanium nanoparticles (GeNPs) are developed as contrast agents for near-infrared-II photoacoustic imaging. The GeNPs are found to have high photothermal stability, good biocompatibility and most importantly, in vivo biodegradability.
Topics & Concepts
BiocompatibilityEx vivoIn vivoPreclinical imagingBiodistributionMaterials scienceBiomedical engineeringFluorescence-lifetime imaging microscopyPhotothermal therapyImaging agentMolecular imagingPhotoacoustic imaging in biomedicineNanotechnologyFluorescenceMedicineOpticsMetallurgyBiologyBiotechnologyPhysicsPhotoacoustic and Ultrasonic ImagingNanoplatforms for cancer theranosticsExtracellular vesicles in disease