Bio-responsive and multi-modality imaging nanomedicine for osteoarthritis theranostics
Song Xue, Guangfeng Ruan, Jia Li, Henning Madry, Chao Zhang, Changhai Ding
Abstract
, photo stimuli, temperature, ultrasound, and magnetic field) responsive nanotherapies. Furthermore, multi-targeted therapeutic strategies combined with multi-modality imaging are also discussed. In general, future exploration of more novel stimuli-responsive nanotherapies that can be used for early diagnosis and cartilage targeting may help ameliorate OA-related cartilage damage, decrease pain, and promote joint function.
Topics & Concepts
OsteoarthritisNanomedicineCartilageMedicineSynovitisPathologicalTherapeutic approachDiseaseBioinformaticsPathologyInternal medicineNanotechnologyArthritisAnatomyBiologyMaterials scienceAlternative medicineNanoparticleOsteoarthritis Treatment and MechanismsChemokine receptors and signalingInflammatory mediators and NSAID effects