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Association of C677T and A1298C polymorphisms of the MTHFR gene with maternal risk for Down syndrome: A meta-analysis of case-control studies

Carla Talita Azevedo Ginani, Jefferson Romáryo Duarte da Luz, Kleyton Santos de Medeiros, Ayane Cristine Alves Sarmento, Fabio Coppedè, Maria das Graças Almeida

2023Mutation Research/Reviews in Mutation Research13 citationsDOI

Topics & Concepts

Methylenetetrahydrofolate reductaseMeta-analysisAlleleConfidence intervalGenetic associationGenetic modelGeneticsCase-control studySubgroup analysisMedicineDemographyInternal medicineOncologyBiologyGenotypeGeneSingle-nucleotide polymorphismSociologyFolate and B Vitamins ResearchDown syndrome and intellectual disability researchPrenatal Screening and Diagnostics
Association of C677T and A1298C polymorphisms of the MTHFR gene with maternal risk for Down syndrome: A meta-analysis of case-control studies | Litcius