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A self-immobilizing near-infrared fluorogenic probe for sensitive imaging of extracellular enzyme activity <i>in vivo</i>

Yuyao Li, Heng Song, Chenghong Xue, Zhijun Fang, Liqin Xiong, Hexin Xie

2020Chemical Science57 citationsDOIOpen Access PDF

Abstract

A novel self-immobilizing and near-infrared fluorogenic probe has been reported to visualize extracellular enzyme activity in living mouse.

Topics & Concepts

In vivoExtracellularEnzymeChemistryEnzyme assayInfraredBiophysicsBiochemistryBiologyOpticsBiotechnologyPhysicsProtein Tyrosine PhosphatasesSupramolecular Self-Assembly in MaterialsFluorine in Organic Chemistry
A self-immobilizing near-infrared fluorogenic probe for sensitive imaging of extracellular enzyme activity <i>in vivo</i> | Litcius