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Development of selective HDAC6 inhibitors with in vitro and in vivo anti-multiple myeloma activity

Shunda Li, Chunlong Zhao, Guozhen Zhang, Qifu Xu, Qian Liu, Wei Zhao, C. James Chou, Yingjie Zhang

2021Bioorganic Chemistry24 citationsDOI

Topics & Concepts

HDAC6In vivoChemistryBortezomibCell cultureIn vitroCancer researchMultiple myelomaPharmacologyKinaseCytotoxicityBiochemistryHistone deacetylaseHistoneBiologyImmunologyGeneGeneticsBiotechnologyHistone Deacetylase Inhibitors ResearchProtein Degradation and InhibitorsPeptidase Inhibition and Analysis
Development of selective HDAC6 inhibitors with in vitro and in vivo anti-multiple myeloma activity | Litcius