Design, synthesis, biological evaluation and molecular docking study of new pyrazolo[1,5-a]pyrimidines as PIM kinase inhibitors and apoptosis inducers
Fatma G. Abdulrahman, Rehab Sabour, Shimaa M. Abd El‐Gilil, Ahmed B. M. Mehany, Enas A. Taha
Topics & Concepts
ChemistryPyrimidineStereochemistryDocking (animal)PyrazoleKinaseEnzymeIC50CytotoxicityPyrimidine analogueApoptosisIn vitroBiochemistryNursingMedicineCancer Mechanisms and TherapySynthesis and biological activitySynthesis and Characterization of Heterocyclic Compounds