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Extending field-of-view of retinal imaging by optical coherence tomography using convolutional Lissajous and slow scan patterns

Shuichi Makita, Shinnosuke Azuma, Toshihiro Mino, Tatsuo Yamaguchi, Masahiro Miura, Yoshiaki Yasuno

2022Biomedical Optics Express12 citationsDOIOpen Access PDF

Abstract

Optical coherence tomography (OCT) is a high-speed non-invasive cross-sectional imaging technique. Although its imaging speed is high, three-dimensional high-spatial-sampling-density imaging of in vivo tissues with a wide field-of-view (FOV) is challenging. We employed convolved Lissajous and slow circular scanning patterns to extend the FOV of retinal OCT imaging with a 1-µm, 100-kHz-sweep-rate swept-source OCT prototype system. Displacements of sampling points due to eye movements are corrected by post-processing based on a Lissajous scan. Wide FOV three-dimensional retinal imaging with high sampling density and motion correction is achieved. Three-dimensional structures obtained using repeated imaging sessions of a healthy volunteer and two patients showed good agreement. The demonstrated technique will extend the FOV of simple point-scanning OCT, such as commercial ophthalmic OCT devices, without sacrificing sampling density.

Topics & Concepts

Lissajous curveOptical coherence tomographyOpticsSampling (signal processing)Field of viewComputer scienceCoherence (philosophical gambling strategy)Preclinical imagingComputer visionArtificial intelligencePhysicsDetectorBiotechnologyBiologyIn vivoQuantum mechanicsOptical Coherence Tomography ApplicationsRetinal and Macular SurgeryRetinal Diseases and Treatments
Extending field-of-view of retinal imaging by optical coherence tomography using convolutional Lissajous and slow scan patterns | Litcius