Evaluation of sulfonate and sulfamate derivatives possessing benzofuran or benzothiophene nucleus as inhibitors of nucleotide pyrophosphatases/phosphodiesterases and anticancer agents
Hanan S. Anbar, Randa El‐Gamal, Saif Ullah, Seyed–Omar Zaraei, Mariya al‐Rashida, Sumera Zaib, Julie Pelletier, Jean Sévigny, Jamshed Iqbal, Mohammed I. El–Gamal
Topics & Concepts
ChemistryLipinski's rule of fiveDocking (animal)PhosphodiesteraseBiochemistryBenzothiopheneXenoestrogenActive siteBenzofuranStereochemistryPharmacologyEnzymeCancerIn silicoMedicineGeneEstrogen receptorOrganic chemistryBreast cancerNursingInternal medicineThiophenePneumocystis jirovecii pneumonia detection and treatmentCoagulation, Bradykinin, Polyphosphates, and AngioedemaAdenosine and Purinergic Signaling