Enasidenib plus azacitidine versus azacitidine alone in patients with newly diagnosed, mutant-IDH2 acute myeloid leukaemia (AG221-AML-005): a single-arm, phase 1b and randomised, phase 2 trial
Courtney D. DiNardo, Andre C. Schuh, Eytan M. Stein, Pau Montesinos, Andrew H. Wei, Stéphane de Botton, Amer M. Zeidan, Amir T. Fathi, Hagop M. Kantarjian, John M. Bennett, Mark G. Frattini, Patricia Martin‐Regueira, Frederik Lersch, Jing Gong, Maroof Hasan, Paresh Vyas, Hartmut Döhner
Topics & Concepts
AzacitidineMedicineIDH2Internal medicineMyeloid leukaemiaPopulationClinical endpointMyeloid leukemiaOncologyMyeloidClinical trialSurgeryIDH1MutantBiologyBiochemistryDNA methylationGene expressionGeneEnvironmental healthAcute Myeloid Leukemia ResearchEpigenetics and DNA MethylationAcute Lymphoblastic Leukemia research