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Villosol reverses 5-FU resistance in colorectal cancer by inhibiting the CDKN2A gene regulated TP53-PI3K/Akt signaling axis

Han Chen, Jiao Deng, Tiewei Hou, Yongqi Shan

2024Journal of Ethnopharmacology14 citationsDOI

Topics & Concepts

CDKN2API3K/AKT/mTOR pathwayProtein kinase BCancer researchColorectal cancerMedicineCancerPharmacologySignal transductionBiologyInternal medicineCell biologyBerberine and alkaloids researchNatural product bioactivities and synthesisGenomics, phytochemicals, and oxidative stress
Villosol reverses 5-FU resistance in colorectal cancer by inhibiting the CDKN2A gene regulated TP53-PI3K/Akt signaling axis | Litcius