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Characterization of an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase to treat Candida albicans infections

Xueyang Jin, Xuben Hou, Xue Wang, Ming Zhang, Jinyao Chen, Minghui Song, Jiaozhen Zhang, Hongbo Zheng, Wenqiang Chang, Hong‐Xiang Lou

2023Cell chemical biology21 citationsDOI

Topics & Concepts

Candida albicansAzoleCorpus albicansSterolMicrobiologyFungal proteinBiologyAllosteric regulationChemistryEnzymeBiochemistryYeastSaccharomyces cerevisiaeAntifungalCholesterolAntifungal resistance and susceptibilityAntimicrobial Peptides and ActivitiesMicrobial Natural Products and Biosynthesis
Characterization of an allosteric inhibitor of fungal-specific C-24 sterol methyltransferase to treat Candida albicans infections | Litcius