Dolomiaea souliei ethyl acetate extract protected against α-naphthylisothiocyanate-induced acute intrahepatic cholestasis through regulation of farnesoid x receptor-mediated bile acid metabolism
Fancheng Meng, Wei Zong, Xiaodong Wei, Yun-Yi Tao, Guowei Wang, Zhihua Liao, Min Chen
Topics & Concepts
Farnesoid X receptorCholestasisUrsodeoxycholic acidBile Salt Export PumpCholesterol 7 alpha-hydroxylaseBile acidG protein-coupled bile acid receptorCYP27A1Multidrug resistance-associated protein 2ChemistryInternal medicineSmall heterodimer partnerEndocrinologyPharmacologyBiochemistryBiologyNuclear receptorMedicineTranscription factorTransporterGeneATP-binding cassette transporterDrug Transport and Resistance MechanismsPharmacological Effects of Medicinal PlantsLiver physiology and pathology