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Safranal alleviates pentetrazole-induced epileptic seizures in mice by inhibiting the NF-κB signaling pathway and mitochondrial-dependent apoptosis through GSK-3β inactivation

Jieping Yan, Tingting Li, Kaiyue Ji, Xinyue Zhou, Weiyi Yao, Liujing Zhou, Ping Huang, Kai Zhong

2024Journal of Ethnopharmacology18 citationsDOI

Topics & Concepts

SafranalCrocus sativusNeuroprotectionApoptosisPharmacologyInflammationNF-κBCrocinEpilepsyMedicineTraditional medicineBiologyChemistryBiochemistryImmunologyNeuroscienceSaffron Plant Research StudiesNeurological Disease Mechanisms and TreatmentsHops Chemistry and Applications
Safranal alleviates pentetrazole-induced epileptic seizures in mice by inhibiting the NF-κB signaling pathway and mitochondrial-dependent apoptosis through GSK-3β inactivation | Litcius