Maintenance olaparib in patients with platinum-sensitive relapsed ovarian cancer: Outcomes by somatic and germline BRCA and other homologous recombination repair gene mutation status in the ORZORA trial
Sandro Pignata, Amit M. Oza, Geoff Hall, Beatriz Pardo, Radosław Mądry, David Cibula, Jaroslav Klát, Ana Fernández Montés, Rosalind Glasspool, Nicoletta Colombo, Imre Pete, Ana Herrero Ibañez, Margarita Romeo Marín, Rumyana Ilieva, Constanta Timcheva, Massimo Di Maïo, Christopher Blakeley, Rosie Taylor, Alan Barnicle, Andrew R. Clamp
Topics & Concepts
MedicineOlaparibTolerabilityOncologyInternal medicineBRCA mutationOvarian cancerCancerAdverse effectPolymeraseGeneChemistryBiochemistryPoly ADP ribose polymerasePARP inhibition in cancer therapyOvarian cancer diagnosis and treatmentBRCA gene mutations in cancer