Design, synthesis, anticancer evaluation and molecular docking studies of chalcone linked pyrido[4,3-b]pyrazin-5(6H)-one derivatives
Dandamudi Srilaxmi, Reddymasu Sreenivasulu, Kit‐Kay Mak, Mallikarjuna Rao Pichika, Surender Singh Jadav, Mohamed Jawed Ahsan, Mandava Venkata Basaveswara Rao
Topics & Concepts
ChemistryChalconeMoietyStereochemistryDocking (animal)MTT assayResidue (chemistry)EtoposideCarbon-13 NMRCancer cellCombinatorial chemistryIn vitroBiochemistryCancerMedicineChemotherapySurgeryInternal medicineNursingSynthesis and biological activityCancer therapeutics and mechanismsBioactive Compounds and Antitumor Agents