Allosteric kidney-type glutaminase (GLS) inhibitors with a mercaptoethyl linker
Bridget Duvall, Sarah C. Zimmermann, Run-Duo Gao, Ajit G. Thomas, Filip Kalčic, Vijayabhaskar Veeravalli, Amira Elgogary, Rana Rais, Camilo Rojas, Anne Le, Barbara S. Slusher, Takashi Tsukamoto
Topics & Concepts
LinkerAllosteric regulationChemistryGlutaminaseMoietyStereochemistryLigand efficiencyBiochemistryLigand (biochemistry)EnzymeReceptorGlutamate receptorComputer scienceOperating systemBiochemical and Molecular ResearchHIV/AIDS drug development and treatmentPneumocystis jirovecii pneumonia detection and treatment