Dexmedetomidine exerts a protective effect on ischemic brain injury by inhibiting the P2X7R/NLRP3/Caspase-1 signaling pathway
Ke Sun, Jiangang Zhang, Qingcheng Yang, Jinzhao Zhu, Xiangdong Zhang, Kun Wu, Zhenhua Li, Weizheng Xie, Xue Luo
Topics & Concepts
PyroptosisMicrogliaPharmacologyMedicineDexmedetomidineCaspase 1In vivoChemistryInflammasomeInflammationInternal medicineBiologySedationBiotechnologyInflammasome and immune disordersNeuroinflammation and Neurodegeneration MechanismsHeme Oxygenase-1 and Carbon Monoxide