Recommendations for the Clinical Approach to Immune Thrombocytopenia: Spanish ITP Working Group (GEPTI)
María Eva Mingot‐Castellano, Mariana Canaro Hirnyk, Blanca Sánchez‐González, María Román, Abelardo Bárez, Ángel Bernardo, Silvia Bernat-Pablo, Estefanía Bolaños-Calderón, Nora Butta, Gonzalo Caballero‐Navarro, Isabel Socorro Caparrós-Miranda, Laura Entrena‐Ureña, Luis Fernando Fernández‐Fuertes, Luis J. Garcia‐Frade, María Gómez del Castillo, Tomás José González‐López, Carlos Grande-García, José María Guinea de Castro, Isidro Jarque‐Ramos, Reyes Jiménez‐Bárcenas, Elsa López‐Ansoar, Daniel Martínez‐Carballeira, Violeta Martínez‐Robles, Emilio Monteagudo-Montesinos, José A. Páramo, María del Mar Perera-Álvarez, Inmaculada Soto, David Valcárcel-Ferreiras, Cristina Pascual
Abstract
Primary immune thrombocytopenia (ITP) is a complex autoimmune disease whose hallmark is a deregulation of cellular and humoral immunity leading to increased destruction and reduced production of platelets. The heterogeneity of presentation and clinical course hampers personalized approaches for diagnosis and management. In 2021, the Spanish ITP Group (GEPTI) of the Spanish Society of Hematology and Hemotherapy (SEHH) updated a consensus document that had been launched in 2011. The updated guidelines have been the reference for the diagnosis and management of primary ITP in Spain ever since. Nevertheless, the emergence of new tools and strategies makes it advisable to review them again. For this reason, we have updated the main recommendations appropriately. Our aim is to provide a practical tool to facilitate the integral management of all aspects of primary ITP management.