Gallium Mesoporphyrin IX-Mediated Photodestruction: A Pharmacological Trojan Horse Strategy To Eliminate Multidrug-Resistant <i>Staphylococcus aureus</i>
Klaudia Michalska, Michał Rychłowski, Martyna Krupińska, Grzegorz Szewczyk, Tadeusz Sarna, Joanna Nakonieczna
Abstract
MPIX-mediated aPDI phenotype. This indicates that changes within the metalloporphyrin structure (vinyl vs ethyl groups) did not significantly alter the properties of recognition of the compound but influenced its biophysical properties.
Topics & Concepts
ChemistryPhototoxicityPhotodynamic therapyStaphylococcus aureusAntimicrobialEffluxPhotosensitizerCytotoxicityLigand (biochemistry)ReceptorBiophysicsIn vitroMicrobiologyBiochemistryBacteriaPhotochemistryBiologyGeneticsOrganic chemistryPhotodynamic Therapy Research StudiesNanoplatforms for cancer theranosticsbioluminescence and chemiluminescence research