Reprogramming of the tumor microenvironment using a PCN-224@IrNCs/<scp>d</scp>-Arg nanoplatform for the synergistic PDT, NO, and radiosensitization therapy of breast cancer and improving anti-tumor immunity
Yi‐Ming Zou, Rong-Tian Li, Lei Yu, Ting Huang, Jian Peng, Wei Meng, Bin Sun, Wen‐Hua Zhang, Zhi‐Hong Jiang, Jun Chen, Jin-Xiang Chen
Abstract
. The nanocomposite design reported herein represents a new regimen for the treatment of breast cancer through TME reprogramming to exert a synergistic effect for effective cancer therapy and antitumor immunity.
Topics & Concepts
Tumor microenvironmentReprogrammingCancer researchPhotodynamic therapyBreast cancerCancer immunotherapyChemistryCancerImmunotherapyImmune systemImmunologyMedicineTumor cellsCellInternal medicineOrganic chemistryBiochemistryNanoplatforms for cancer theranosticsCancer, Stress, Anesthesia, and Immune ResponseAnesthesia and Neurotoxicity Research